Dakota Blum turned in a game-high 16 for the 9-4 Raiders. Shay Quirk added 11, Shae Blum and Kaitlin Bass eight apiece and Makayla Ernst and Jordan Fisher seven apiece.
The Panther found themselves in a 42-15 hole at the half and would see the continuous clock start running in the fourth quarter.
Jasmine Demers led St. Mary's with 15 points on the night. Riley Lenhart turned in seven, Mackenzie Laven six and Rachel Todd two.
The road gets no easier for the 3-9 Panthers as they ride a five game losing streak into Tuesday's matchup against 3rd-ranked Newell-Fonda.